BDBM50038269 2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL135937
SMILES CC(C)CN1C=CC(C)=C2C(=O)NC(N)N=C12
InChI Key InChIKey=JFHPIYDRBRORCK-UHFFFAOYSA-N
Data 11 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50038269
Affinity DataKd: 30nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
Affinity DataKd: 3.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
Affinity DataKd: 3.00E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
Affinity DataKd: 57nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equations 15 ...More data for this Ligand-Target Pair
Affinity DataKd: 80nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equations 11 a...More data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 16More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair