BDBM50038270 2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL336628

SMILES CC(C)CN1C=CC=C2C(=O)NC(N)N=C12

InChI Key InChIKey=UTLUAUJSXNWJNN-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038270   

TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  600nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed