BDBM50052412 4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-amino]-2,6-difluoro-benzoic acid::CHEMBL439780

SMILES CC1(C)CCC(C)(C)c2c(Br)c(O)c(cc12)C(=O)Nc1cc(F)c(C(O)=O)c(F)c1

InChI Key InChIKey=RMGWEAQQLIKPLW-UHFFFAOYSA-N

Data  6 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50052412   

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  4nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  1.74E+4nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  6.40E+3nMAssay Description:Binding affinity for retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataEC50:  290nMAssay Description:Binding affinity for retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052412(4-[(4-Bromo-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-...)
Affinity DataKd:  8.40nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed