BDBM50062430 9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL104183

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(Cl)ccc4OC(c4cccc(Cl)c4)c3c12

InChI Key InChIKey=YTMMXBWUMWUPPN-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50062430   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.480nMAssay Description:The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity for human progesterone receptor isoform A expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity for human glucocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataEC50:  3.60nMAssay Description:Effective concentration for half-maximal activation of human progesterone receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062430(9-Chloro-5-(3-chloro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataEC50:  3.60nMAssay Description:Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed