BDBM50064333 CHEMBL49860::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-phenyl) ester

SMILES NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)NC(CC(N)=O)C(N)=O

InChI Key InChIKey=YJYFCZXVXPEVDA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064333   

TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)
Affinity DataIC50:  1nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of binding to Growth factor receptor bound protein 2 (Grb2) SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)
Affinity DataIC50:  6.24nMAssay Description:Inhibition of binding to p56 Lck tyrosine kinase SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSHC-transforming protein 2(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)
Affinity DataIC50: >5nMAssay Description:Inhibition of binding to SH2 domain of SHC-PTBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)
Affinity DataIC50: >5nMAssay Description:Inhibition of interaction between the activated tyrosine kinase receptors and Shp2 SH2 domains in the Ras signal transduction pathway.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed