BDBM50064345 (3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcarbamoyl-2,8-dioxo-1,4,9triaza-cyclotetradecane-5-carboxylic acid::CHEMBL48256

SMILES CNC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](N[C@@H](CCc2ccc(cc2)-c2ccccc2)C(=O)N1)C(O)=O

InChI Key InChIKey=DOXXSEYJDIFFAY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064345   

TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  9nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  249nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  288nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064345((3S,5R,14S)-3-(2-Biphenyl-4-yl-ethyl)-14-methylcar...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed