BDBM50071864 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid amide::CHEMBL2370163

SMILES CC1(C)SSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O

InChI Key InChIKey=VDYOLQMTBBHOCK-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071864   

TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataEC50:  18nMAssay Description:Compound was tested for its ability to stimulate [35S]GTP-gamma-S, binding to membranes from C6 glioma cells stably expressing rat mu opioid receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  7nMAssay Description:Binding affinity against mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  58nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50071864(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed