BDBM50084617 ((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid::CHEMBL20240::YM-60828
SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(=O)(=O)CC(O)=O
InChI Key InChIKey=NPBKHEMDWREFJJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50084617
Affinity DataKi: 1.30nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity against Coagulation factor XChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibitory concentration against human Coagulation factor Xa (fXa)More data for this Ligand-Target Pair
Affinity DataKi: 159nMAssay Description:Inhibitory concentration against bovine trypsinMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Portola Pharmaceuticals
Curated by ChEMBL
Portola Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against Thrombin.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse FXaMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibitory concentration against prothrombinChecked by AuthorMore data for this Ligand-Target Pair