BDBM50088378 Afinitor::Afinitor Disperz::CHEBI:68478::Everolimus::RAD001::US12091424, Example RAD001::Zortress

SMILES [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OCCO)[C@@H](C1)OC

InChI Key InChIKey=HKVAMNSJSFKALM-UHFFFAOYSA-N

Data  20 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088378   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50088378(CHEBI:68478 | Afinitor | Afinitor Disperz | Everol...)
Affinity DataKd:  2nMAssay Description:Binding affinity to mTOR FKBP12 site (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed