BDBM50095596 CHEMBL70222::[4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl)-methanone

SMILES Brc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCN(CC1)c1ccncc1

InChI Key InChIKey=NTEVEFOEWIWAOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095596   

TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,...)
Affinity DataIC50: 161nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,...)
Affinity DataIC50: 228nMAssay Description:In vitro inhibitory activity of the compound against rat microsomal 2,3-Oxidosqualene lanosterol cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,...)
Affinity DataIC50: 228nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed