BDBM50101446 (2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-penta-2,4-dienoic acid::3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-penta-2,4-dienoic acid::CHEMBL308377

SMILES C\C(\C=C\[C@H]1C[C@@]1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O

InChI Key InChIKey=BOOOLEGQBVUTKC-DHPCXDHDSA-N

Data  8 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50101446   

TargetRetinoic acid receptor beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  6.20E+3nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd: >10nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  210nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd: >1.00E+4nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  5.75E+3nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  180nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  60nMAssay Description:Dissociation constant for Retinoid X receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50101446((2E,4E)-3-Methyl-5-[(1R,2R)-2-methyl-2-(5,5,8,8-te...)
Affinity DataKd:  60nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed