BDBM50103521 Actos::CHEBI:8228::Duetact::Pioglitazone::US10188639, Compound h-rac-pio::US11141411, Compound h-rac-pio::US20240091210, Compound Pioglitazone

SMILES CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1

InChI Key InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N

Data  11 KI  21 IC50  2 Kd  31 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103521   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US10...)
Affinity DataIC50: 262nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed