BDBM50103521 Actos::CHEBI:8228::Duetact::Pioglitazone::US20240091210, Compound Pioglitazone

SMILES CCc1ccc(nc1)CCOc2ccc(cc2)C[C@@H]3C(=O)NC(=O)S3

InChI Key InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N

Data  11 KI  21 IC50  2 Kd  29 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103521   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Fuji Research Park, R&D Division

Curated by ChEMBL
LigandPNGBDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataEC50:  2.05E+3nMAssay Description:Transactivation of GAL4-fused human PPARgamma transfected in HEK293BENA cells after 24 hrs by steady glo-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)