BDBM50105463 2,7-diamino-10-ethyl-9-phenylphenanthridinium bromide::2,7-diamino-9-phenyl-10-ethylphenanthridinium bromide::3,8-diamino-5-ethyl-6-phenylphenanthridinium bromide::CHEMBL284328::Dromilac::EtBr::Ethidium bromide::Homidium bromide

SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12

InChI Key InChIKey=QTANTQQOYSUMLC-UHFFFAOYSA-O

Data  20 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50105463   

TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of telomerase activity in human CNE-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against telomerase (Compound released from underivatized resinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of telomerase supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory activity against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of telomerase-mediated supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of telomerase activity expressed in human SGC7901 cells by SYBER green dye based TRAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of telomerase in human MDA-MB-231 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed