BDBM50109024 (S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL93753

SMILES O=c1[nH]c2ccc3CC[C@@H](CNCc4ccccc4)Oc3c2[nH]1

InChI Key InChIKey=NJDDOYGAHXQMEQ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109024   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109024((S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-c...)
Affinity DataKi:  5.5nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109024((S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-c...)
Affinity DataKi:  67nMAssay Description:Affinity for the Dopamine receptor D2S was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109024((S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-c...)
Affinity DataKi:  68nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109024((S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-c...)
Affinity DataKi:  81nMAssay Description:Affinity for the Human Dopamine receptor D3 was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109024((S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-c...)
Affinity DataKi:  313nMAssay Description:Affinity for the Human Dopamine receptor D4 was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed