BDBM50133122 5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biphenyl-2-yl]-3-methyl-penta-2,4-dienoic acid::CHEMBL130230

SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1ccccc1\C=C\C(\C)=C\C(O)=O

InChI Key InChIKey=CYIQJMUSSBGDPA-RJXLRZCOSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50133122   

TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi:  42nMAssay Description:Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi:  74nMAssay Description:Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor, alpha, isoform CRA_b(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for Retinoic acid receptor alpha was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for peroxisome Peroxisome proliferator activated receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for Retinoic acid receptor beta was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor, gamma(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for Retinoic acid receptor gamma was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133122(5-[2'-(2,2-Difluoro-ethoxy)-3',5'-diisopropyl-biph...)
Affinity DataIC50:  80nMAssay Description:Invitro evaluation against RXR-alpha in CV-1 cells by cotransfection assay was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed