BDBM50135836 1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3H-imidazol-1-ium::CHEMBL340034::ZOLEDRONIC ACID

SMILES OC(C[n+]1cc[nH]c1)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=OVARJRDCUIDTGY-UHFFFAOYSA-O

Data  1 KI  2 IC50

PDB links: 20 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135836   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135836(1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3H-imidazol-...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135836(1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3H-imidazol-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135836(1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3H-imidazol-...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair