BDBM50138819 CHEMBL3753837::US10233190, Example 1357

SMILES OC(CC1c2c(cccc2F)-c2cncn12)C1CCCCC1

InChI Key InChIKey=AKOIXTSNUPHRQM-UHFFFAOYSA-N

Data  7 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138819   

TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50138819(CHEMBL3753837 | US10233190, Example 1357)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human IDO1 assessed as conversion of N-formylkynurenine to kynurenine incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50138819(CHEMBL3753837 | US10233190, Example 1357)
Affinity DataEC50:  55nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed