BDBM50152551 4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid::CHEMBL185257

SMILES OC(=O)C(=O)CC(=O)c1ccc(o1)-c1ccccc1Cl

InChI Key InChIKey=GKIOHUBKQAKOEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152551   

TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152551(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.85E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152551(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.22E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed