BDBM50163860 CHEMBL3797893::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 16

SMILES C1CCN(CC1)c2c(c(c(c(c2F)F)S(=O)(=O)N)F)F

InChI Key InChIKey=VVFJHOCIYNHEFY-UHFFFAOYSA-N

Data  16 Kd  10 Koff  5 Kon

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163860   

TargetCarbonic anhydrase 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163860(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  0.0290nMAssay Description:Binding affinity to human recombinant CA1 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)