BDBM50170194 CHEMBL367355::trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzamide

SMILES CN(C)c1nc(NCC2CCC(CNC(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12

InChI Key InChIKey=KENQBAJESGJICP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170194   

TargetAlpha-2A adrenergic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170194(trans-4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-...)
Affinity DataIC50: 9.90nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed