BDBM50178925 9-cyclopropyl-6-fluoro-7-(3-(piperidin-2-yl)phenyl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione::CHEMBL438444

SMILES Fc1cc2c(cc1-c1cccc(c1)C1CCCCN1)n(C1CC1)c1s[nH]c(=O)c1c2=O

InChI Key InChIKey=PKSRQRFDRMZEJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178925   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178925BDBM50178925(9-cyclopropyl-6-fluoro-7-(3-(piperidin-2-yl)phenyl...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed