BDBM50189911 CHEMBL3827611
SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1)O2
InChI Key InChIKey=SBKJRDAJADZOCH-XGBSXSJOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50189911
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 176nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 519nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC5 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxy...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled acetylat...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HDAC7 (518 to end residues) expressed in baculovirus coexpressed in fall armyworm Sf9 cells usi...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC9 (604 to 1066 residues) expressed in baculovirus coexpressed in fall armyworm Sf9 cells us...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged and C-terminal His-tagged human recombinant HDAC4 (627 to 1084 residues ) expressed in baculovirus coexpressed in...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxy...More data for this Ligand-Target Pair