BDBM50189911 CHEMBL3827611

SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1)O2

InChI Key InChIKey=SBKJRDAJADZOCH-XGBSXSJOSA-N

Data  2 KI  9 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50189911   

TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataKi:  176nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataKi:  519nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC5 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled acetylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HDAC7 (518 to end residues) expressed in baculovirus coexpressed in fall armyworm Sf9 cells usi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC9 (604 to 1066 residues) expressed in baculovirus coexpressed in fall armyworm Sf9 cells us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50:  192nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50:  168nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of N-terminal GST-tagged and C-terminal His-tagged human recombinant HDAC4 (627 to 1084 residues ) expressed in baculovirus coexpressed in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189911(CHEMBL3827611)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed