BDBM50200551 CHEMBL3978901

SMILES C(C1CCCCC1)N1CCN(CC1)c1cc(nc(n1)N1CCCC1)N1CCCC1

InChI Key InChIKey=ZMIXZDFAIQPNIS-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200551   

TargetCaspase-1(Human)
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataKi:  27nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetCaspase-1(Human)
Depaul University

Curated by ChEMBL
LigandPNGBDBM50200551(CHEMBL3978901)
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed