BindingDB BDBM50208911 CHEMBL3884319

BDBM50208911 CHEMBL3884319

SMILES CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(Nc3ccccc3)ncc12

InChI Key InChIKey=XLFNLJYGUOLEJS-SFHVURJKSA-N

Data 100 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 100 hits for monomerid = 50208911

Activin receptor type-1B(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged ALK4 catalytic domain (150 to 505 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Inhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged IKKepsilon expressed in baculovirus expression systemMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAP2K6 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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PAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged PASK catalytic domain (879 to 1323 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Protein kinase C theta type(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PRKCQ expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Rho-associated protein kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged ROCK2 cytoplasmic domain (1 to 552 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged ZAP70 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 98nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 591nMAssay Description:Inhibition of human recombinant His-tagged FGFR2 cytoplasmic domain (403 to 822 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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MAP kinase-activated protein kinase 5(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPKAPK5 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Casein kinase II subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged CSNK2A1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.45E+3nMAssay Description:Inhibition of human recombinant His-tagged KDR cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Angiopoietin-1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.04E+3nMAssay Description:Inhibition of human recombinant GST-tagged TEK cytoplasmic domain (817 to 1101 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 2.22E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged MST4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Inhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged IKKbeta expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged TYK2 cytoplasmic domain (833 to 1187 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged TBK1 expressed in insect expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 12nMAssay Description:Inhibition of human recombinant His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged IRAK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity protein kinase CLK2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.01E+3nMAssay Description:Inhibition of human recombinant GST-tagged CLK2 catalytic domain (137 to 498 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.15E+3nMAssay Description:Inhibition of human recombinant full length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.17E+3nMAssay Description:Inhibition of human recombinant GST-tagged JAK2 cytoplasmic domain (809 to 1153 +9 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Insulin receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.19E+3nMAssay Description:Inhibition of human recombinant GST-tagged INSR cytoplasmic domain (1011 to 1382 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Mitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.26E+3nMAssay Description:Inhibition of human recombinant GST-tagged MAP3K8 catalytic domain (30 to 397 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Cytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.36E+3nMAssay Description:Inhibition of human recombinant full length His-tagged BMX cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Cyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.58E+3nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/cyclin T1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.88E+3nMAssay Description:Inhibition of human recombinant full length His-tagged BTK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 2.04E+3nMAssay Description:Inhibition of human recombinant full length GST-tagged BRAF expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 2.14E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged IGF1R cytoplasmic domain (960 to 1397 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase Chk2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 2.17E+3nMAssay Description:Inhibition of human recombinant full length His-tagged CHEK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 2.99E+3nMAssay Description:Inhibition of human recombinant full length His-tagged GSK3B expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Testis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 3.12E+3nMAssay Description:Inhibition of human recombinant full length His-tagged STK22D expressed in baculovirus expression systemMore data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 3.16E+3nMAssay Description:Inhibition of human recombinant GST-tagged JAK3 cytoplasmic domain (781 to 1124 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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RAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged AKT2beta expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Calcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged CAMK4 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged CHEK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Death-associated protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DAPK1 catalytic domain (1 to 363 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged ERBB2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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G protein-coupled receptor kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged GRK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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G protein-coupled receptor kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged GRK6 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged JAK1 cytoplasmic domain (866 to 1154 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAP2K1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Mitogen-activated protein kinase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPK9 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged MAPKAPK2 expressed in Escherichia coliMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Misshapen-like kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged MINK1 catalytic domain (1 to 320 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Serine/threonine-protein kinase N1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged PKN1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Serine/threonine-protein kinase PLK1(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PLK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Protein kinase C zeta type(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length PRKCZ expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Protein-tyrosine kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL

BDBM50208911(CHEMBL3884319)

IC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged PTK6 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Displayed 1 to 50 (of 100 total ) | Next | Last >>

Filter my 100 hits

Targets 100▿
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 1
- Tyrosine-protein kinase JAK1 1
- Receptor tyrosine-protein kinase erbB-2 1
- Lysine--tRNA ligase 1
- Hepatocyte growth factor receptor 1
- Non-receptor tyrosine-protein kinase TYK2 1
- Serine/threonine-protein kinase B-raf 1
- Glycogen synthase kinase-3 alpha 1
- Glycogen synthase kinase-3 beta 1
- Serine/threonine-protein kinase Nek6 1
- Protein kinase C iota type 1
- NUAK family SNF1-like kinase 1 1
- Receptor-type tyrosine-protein kinase FLT3 1
- Serine/threonine-protein kinase Nek4 1
- Serine/threonine-protein kinase Nek2 1
- Sphingosine kinase 1 1
- MAP/microtubule affinity-regulating kinase 3 1
- Serine/threonine-protein kinase PAK 1 1
- Protein kinase C theta type 1
- Tyrosine-protein kinase JAK3 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Tyrosine-protein kinase JAK2 1
- MAP/microtubule affinity-regulating kinase 4 1
- Dual specificity mitogen-activated protein kinase kinase 6 1
- Tyrosine-protein kinase ZAP-70 1
- Leucine-rich repeat serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase Sgk1 1
- Ephrin type-A receptor 3 1
- Tyrosine-protein kinase BTK 1
- Tyrosine-protein kinase ITK/TSK 1
- Insulin-like growth factor 1 receptor 1
- Epidermal growth factor receptor 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Ribosomal protein S6 kinase beta-1 1
- Serine/threonine-protein kinase 26 1
- Cyclin-dependent kinase 2 1
- Ephrin type-B receptor 2 1
- MAP kinase-activated protein kinase 2 1
- Ephrin type-A receptor 8 1
- MAP kinase-activated protein kinase 5 1
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1
- Death-associated protein kinase 1 1
- PAS domain-containing serine/threonine-protein kinase 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1
- Beta-adrenergic receptor kinase 1 1
- Serine/threonine-protein kinase pim-1 1
- Serine/threonine-protein kinase TAO2 1
- Testis-specific serine/threonine-protein kinase 1 1
- Angiopoietin-1 receptor 1
- Mast/stem cell growth factor receptor Kit 1
- Serine/threonine-protein kinase MRCK alpha 1
- Protein-tyrosine kinase 6 1
- Mitogen-activated protein kinase 14 1
- Activin receptor type-1B 1
- Casein kinase II subunit alpha 1
- Cyclin-dependent kinase 5 activator 1 1
- Interleukin-1 receptor-associated kinase 4 1
- Cytoplasmic tyrosine-protein kinase BMX 1
- RAC-gamma serine/threonine-protein kinase 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1 1
- Interleukin-1 receptor-associated kinase 1 1
- Mitogen-activated protein kinase kinase kinase 8 1
- Tyrosine-protein kinase ABL1 1
- RAC-alpha serine/threonine-protein kinase 1
- Rho-associated protein kinase 2 1
- Rho-associated protein kinase 1 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Mitogen-activated protein kinase 1 1
- Tyrosine-protein kinase Lck 1
- CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 1
- NT-3 growth factor receptor 1
- Mitogen-activated protein kinase 9 1
- G protein-coupled receptor kinase 4 1
- Dual specificity protein kinase CLK2 1
- High affinity nerve growth factor receptor 1
- G protein-coupled receptor kinase 6 1
- Mitogen-activated protein kinase 8 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Serine/threonine-protein kinase N1 1
- Ribosomal protein S6 kinase alpha-3 1
- Serine/threonine-protein kinase TBK1 1
- Cyclin-T1/Cyclin-dependent kinase 9 1
- Aurora kinase B 1
- Vascular endothelial growth factor receptor 2 1
- Insulin receptor 1
- Tyrosine-protein kinase HCK 1
- Fibroblast growth factor receptor 2 1
- Serine/threonine-protein kinase PLK1 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta 1
- Mitogen-activated protein kinase 13 1
- RAC-beta serine/threonine-protein kinase 1
- Casein kinase I isoform alpha 1
- Misshapen-like kinase 1 1
- Macrophage colony-stimulating factor 1 receptor 1
- cAMP-dependent protein kinase catalytic subunit alpha 1
- Protein kinase C zeta type 1
- Serine/threonine-protein kinase Chk2 1
- Serine/threonine-protein kinase Chk1 1
- SRSF protein kinase 1 1
Publications 1▿
- Bioorg Med Chem Lett 27: 114-120 (2017) 100
Institutions 1▿
- Merck 100
Affinity: 1.2 to 1.0E+4 nM▿
- IC50 100
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0