BDBM50210256 CHEMBL26300::Sulfamic acid (3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-tetrahydro-benzo[1,2-d;3,4-d']bis[1,3]dioxol-3a-ylmethyl ester::Topiramate, 3

SMILES CC1(C)O[C@@H]2CC[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key InChIKey=DIISHYBDWUTJIE-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210256   

TargetCarbonic anhydrase 4(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  4.90E+3nM ΔG°:  -7.12kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed