BDBM50214930 5-[1-biphenyl-4-yl-meth-(Z)-ylidene]-10-methoxy-2,2,4-trimethyl-2,4a,5,12a-tetrahydro-1H-6-oxa-1-aza-chrysen-9-ol::CHEMBL437556
SMILES COc1c(O)ccc2O\C(=C/c3ccc(cc3)-c3ccccc3)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=ZBMDLEOBRDEIKO-VEILYXNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214930
Affinity DataKi: 4.40nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair