BDBM50233612 CHEMBL4102348::US10882838, Example 1.7

SMILES [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCCCBr

InChI Key InChIKey=KLFIJAPNCYROCE-IAGOWNOFSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50233612   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Northeastern University

US Patent
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  0.600nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Northeastern University

US Patent
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  0.800nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(MOUSE)
Northeastern University

US Patent
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  1.10nMAssay Description:All the cannabinoids discussed in this invention are tested for their ability to bind to CB1 and CB2 receptors using membranes from rat brain or HEK2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(MOUSE)
Northeastern University

US Patent
LigandPNGBDBM50233612(CHEMBL4102348 | US10882838, Example 1.7)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cells by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed