BDBM50233639 CHEMBL4097104

SMILES O=C(COc1ccc(cc1)-n1ccnc1)Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VHJQAYMEVPBDIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233639   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233639(CHEMBL4097104)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293-STF3A cells assessed as inhibition of Wnt signaling by measuring decrease in beta-cateni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233639(CHEMBL4097104)
Affinity DataIC50: 20nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233639(CHEMBL4097104)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2019
Entry Details Article
PubMed
TargetStefin-3(Mouse)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50233639(CHEMBL4097104)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse STF3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed