BDBM50239492 CHEMBL4070515::US10329302, Example 211::US10793579, Example 211::US11702424, Example 211

SMILES COc1cc2c(OC[C@H]3NC(=O)C[C@H]3C)nccc2cc1C(N)=O

InChI Key InChIKey=SIANUOWPRWUGIU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239492   

LigandChemical structure of BindingDB Monomer ID 50239492BDBM50239492(CHEMBL4070515 | US10329302, Example 211 | US107935...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full-length IRAK4 (unknown origin) in presence of ATP by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50239492BDBM50239492(CHEMBL4070515 | US10329302, Example 211 | US107935...)
Affinity DataIC50: 52nMAssay Description:Inhibition of IRAK4 in human PBMC cells assessed as reduction in R848-stimulated TNF-alpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed