BDBM50239947 CHEMBL4089730::US20230303494, Compound BMS202::US20240043392, Compound BMS-202::US20240327387, Compound BMS202::US9872852, Example 202

SMILES COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O

InChI Key InChIKey=JEDPSOYOYVELLZ-UHFFFAOYSA-N

Data  50 IC50  4 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50239947   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) protein-protein interaction incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 17nMAssay Description:Inhibition of europium-labeled PD-1/biotinylated PD-L1 interaction (unknown origin) preincubated for 15 mins with PD-L1 followed by PD-1 addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataKd:  1.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin) protein-protein interaction measured after 135 mins by TR-FRET assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PD1/PDL1 interaction (unknown origin) after 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) preincubated with PD-L1 for 15 mins followed by PD-1 addition measured after 90 mins by TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as disruption of PD-1/PD-L1 complex incubated for 2 hrs by Tag-1 Eu3+ and anti-Tag2-XL665 based H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed