BDBM50244760 (E)-4-{3-[3-Adamantan-1-yl-4-(2-methoxy-ethoxymethoxy)-phenyl]-3-oxo-propenyl}-benzoic acid::4-{3-[3-Adamantan-1-yl-4-(2-methoxy-ethoxymethoxy)-phenyl]-3-oxo-propenyl}-benzoic acid::CHEMBL462134

SMILES COCCOCOc1ccc(cc1C12CC3CC(CC(C3)C1)C2)C(=O)\C=C\c1ccc(cc1)C(O)=O

InChI Key InChIKey=JSLORBCSMVYNTA-XBXARRHUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244760   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50244760((E)-4-{3-[3-Adamantan-1-yl-4-(2-methoxy-ethoxymeth...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of purified recombinant histidine-HA-tagged IKKbeta (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50244760((E)-4-{3-[3-Adamantan-1-yl-4-(2-methoxy-ethoxymeth...)
Affinity DataIC50:  4.47E+3nMAssay Description:Antagonist activity at Gal4-fused RARalpha (unknown origin) transfected in HEK293 cells assessed as inhibition of ATRA-induced transcriptional activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50244760((E)-4-{3-[3-Adamantan-1-yl-4-(2-methoxy-ethoxymeth...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of recombinant IKKbeta (unknown origin) using ulight-IkappaomegaBalpha as substrate after 2 hrs by LANCE ultra TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed