BDBM50245853 CHEMBL502156::N3-(2,6-dimethylphenyl)-N6-(3-fluoro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxy-3-methylbutyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
SMILES COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(OCCN4CCCC4)c(F)c3)nc12
InChI Key InChIKey=CLLDBMRRUZYRLR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50245853
Affinity DataKi: 3nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+4nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of ACK1 (unknown origin) by cellular mechanistic assayMore data for this Ligand-Target Pair