BDBM50255958 6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methylsulfonyl)piperazin-1-yl)-1H-imidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridine::CHEMBL480583

SMILES Cc1nc(ccc1F)-c1nc([nH]c1-c1ccc2ncnn2c1)N1CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=BJFZENQVDHGYIC-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255958   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataEC50:  4.12E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50255958(6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methyls...)
Affinity DataEC50:  414nMAssay Description:Inhibition of TGFBR1 (unknown origin) transfected in human HepG2 cells after 24 hrs by plasminogen activator inhibitor-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed