BDBM50259570 CHEMBL4102871

SMILES CC(=O)Nc1cccc(Nc2ccc3ncc(-c4cccc(NC(C)=O)c4)n3n2)c1

InChI Key InChIKey=WEQRXDXDFLBIDK-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50259570   

TargetDual specificity protein kinase CLK2(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  30nMAssay Description:Inhibition of GST tagged recombinant mouse CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  520nMAssay Description:Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  65nMAssay Description:Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  61nMAssay Description:Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  40nMAssay Description:Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  63nMAssay Description:Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  580nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259570(CHEMBL4102871)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed