BDBM50278872 CHEMBL4170755

SMILES [H][C@@]1(CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)C=Cc1cc[n+](C)cc1

InChI Key InChIKey=FVRAVRAHUYIUAC-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278872   

TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278872(CHEMBL4170755)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed