BDBM50286735 CHEMBL4165756

SMILES CC(=O)N1CCC(C[C@H](N2C(=O)CN(C2=O)c2ccc(Oc3ccccc3)cc2)c2nc3ccc(Cl)cc3n2C)CC1

InChI Key InChIKey=LQPNVPFGSAKIGM-LJAQVGFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286735   

TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50286735(CHEMBL4165756)
Affinity DataIC50:  3.50E+3nMAssay Description:Antagonist activity at GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced fluorecein-labeled SRC2-2 coactivator recruitment...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50286735(CHEMBL4165756)
Affinity DataIC50:  3.50E+3nMAssay Description:Antagonist activity at GST-tagged FXR LBD (unknown origin) assessed as inhibition of GW4064-induced fluorecein-labeled SRC2-2 coactivator recruitment...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed