BDBM50290191 3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopent-1-enyl]-penta-2,4-dienoic acid::CHEMBL79234

SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O

InChI Key InChIKey=VYBMNAKWMZVNRX-WDWAOICLSA-N

Data  6 KI  5 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50290191   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-beta(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi:  36nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-gamma(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi:  58nMAssay Description:Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataEC50:  339nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-beta(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataEC50:  42nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataEC50:  1.15E+3nMAssay Description:Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataEC50:  53nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-gamma(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
Show InChI InChI=1S/C25H32O2/c1-17(15-23(26)27)9-10-18-7-6-8-20(18)19-11-12-21-22(16-19)25(4,5)14-13-24(21,2)3/h9-12,15-16H,6-8,13-14H2,1-5H3,(H,26,27)/b10-9+,17-15+
Affinity DataEC50:  40nMAssay Description:Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair