BDBM50342140 3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminophenyl)-propionicAcid Methyl Ester::CHEMBL1766000

SMILES COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1

InChI Key InChIKey=XJNXEEASXBUDAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342140   

TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342140(3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminopheny...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP26A1-mediated retionic acid metabolism in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342140(3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminopheny...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed