BDBM50342141 3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidazol-1-yl-2,2-dimethylpropionicAcid Methyl Ester::CHEMBL1766001

SMILES COC(=O)C(C)(C)C(c1ccc(Nc2ccc3OCOc3c2)cc1)n1ccnc1

InChI Key InChIKey=BKFCTFAONAURHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342141   

TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342141(3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidaz...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CYP26A1-mediated retionic acid metabolism in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342141(3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidaz...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed