BDBM50355491 CHEMBL1835870
SMILES Nc1nc(Nc2ccc(cc2)[C@H]2CC[C@@H](CC2)N2CCOCC2)nn1-c1ccccn1
InChI Key InChIKey=OYUDNKFIGXAIRZ-KESTWPANSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50355491
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of PDGFR-betaMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of c-KIT-mediated ERK 1/2 phosphorylation in human TF1 cells at 4 to 12 nM after 1 hr by immunoblot analysisMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of SCF-induced phosphorylation of c-KIT in human TF1 cells after 1 hr by immunoblot analysisMore data for this Ligand-Target Pair