BDBM50398835 CHEMBL2177521

SMILES N#Cc1ccncc1C1=CC2CNCC(C2)C1

InChI Key InChIKey=CHUVPNWRFUBJRL-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398835   

LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataEC50:  3.25E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398835(CHEMBL2177521)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed