BDBM50398851 CHEMBL2177546

SMILES CN1CC2CC(C1)C=C(C2)c1cncc(Oc2ccccc2)c1

InChI Key InChIKey=JPNUKJAOPRHHRY-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398851   

LigandPNGBDBM50398851(CHEMBL2177546)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398851(CHEMBL2177546)
Affinity DataEC50:  183nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398851(CHEMBL2177546)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50398851(CHEMBL2177546)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed