BDBM50402935 CHEMBL2206223

SMILES CC(O)C1CCN(CC1)c1nccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1

InChI Key InChIKey=GNWKATFENPQMIQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402935   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402935(CHEMBL2206223)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human PDE3A using FAM-cAMP as substrate incubated for 60 mins prior to substrate addition measured after 90 mins by IMAP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402935(CHEMBL2206223)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50402935(CHEMBL2206223)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50402935(CHEMBL2206223)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human PDE10A2 using FAM-cAMP as substrate incubated for 60 mins prior to substrate addition measured after 90 mins by IMAP-FRET assayMore data for this Ligand-Target Pair