BDBM50437341 WITHANOLIDE E

SMILES CC1=C(C)C(=O)O[C@H](C1)[C@](C)(O)[C@]1(O)CC[C@@]2(O)[C@@H]3C[C@H]4O[C@]44CC=CC(=O)[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=RUVPNJSJTWTANE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50437341   

TargetNF-kappa-B inhibitor alpha(Human)
Riken

Curated by ChEMBL
LigandPNGBDBM50437341(WITHANOLIDE E)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of TNFalpha-induced IkappaBalpha (unknown origin) phosphorylation expressed in human HeLa cells pretreated 30 mins before TNFalpha additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50437341(WITHANOLIDE E)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of BRD3-BD1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetBromodomain-containing protein 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50437341(WITHANOLIDE E)
Affinity DataIC50: 720nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetBromodomain-containing protein 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50437341(WITHANOLIDE E)
Affinity DataIC50: 556nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetBromodomain-containing protein 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50437341(WITHANOLIDE E)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed