BDBM50459311 CHEMBL1922604::FR900098

SMILES CC(=O)N(O)CCCP(O)([O-])=O

InChI Key InChIKey=LCFXFDGYDKNWMD-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459311   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50: 23nMAssay Description:Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
George Washington University

Curated by ChEMBL
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50: 24nMAssay Description:Inhibition of Plasmodium falciparum DXRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Staphylococcus hyicus subsp. chromogenes)
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50: 360nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase()
THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION; WASHINGTON UNIVERSITY

US Patent
LigandPNGBDBM50459311(CHEMBL1922604 | FR900098)
Affinity DataIC50: 1.00E+3nMAssay Description:Oxidation of NADPH to NADP+ as a result of substrate turnover was monitored at 340 nm in a POLARstar Omega microplate reader (BMG Labtech). The stand...More data for this Ligand-Target Pair
In DepthDetails
US Patent