BDBM50466622 CHEMBL4286209

SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)C(Cl)Cl

InChI Key InChIKey=NWWAQIKCANAFJE-UHFFFAOYSA-N

Data  4 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50466622   

TargetRetinal dehydrogenase 2(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataKi:  5.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataKi:  64nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human RALDH2 using RAL as substrate measured after 30 mins in presence of NADH by Morrison's plot an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataKi:  128nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells up to 500 nM using RAL as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAldehyde dehydrogenase 1A1(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataKi:  194nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH1 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate measured after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed