BDBM50469457 CHEMBL4286698

SMILES Nc1cc(C(F)F)c(cn1)-c1nc(nc(n1)N1C2CCC1COC2)N1C2CCC1COC2

InChI Key InChIKey=UGDKPWVVBKHRDK-UHFFFAOYSA-N

Data  4 KI  2 IC50  14 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469457   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  2.75E+3nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  2.75E+3nMAssay Description:Binding affinity to human wild-type partial length VPS34 (S282 to H879 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed