BDBM50469457 CHEMBL4286698

SMILES Nc1cc(C(F)F)c(cn1)-c1nc(nc(n1)N1C2CCC1COC2)N1C2CCC1COC2

InChI Key InChIKey=UGDKPWVVBKHRDK-UHFFFAOYSA-N

Data  4 KI  2 IC50  14 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469457   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataIC50: 190nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed