BDBM50503240 CHEMBL4445651

SMILES Nc1nc2[nH]c(CCCc3csc(C(=O)N[C@@H](CCC(O)=O)C(O)=O)c3F)cc2c(=O)[nH]1

InChI Key InChIKey=WMTFSFGBNBUALY-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503240   

TargetReduced folate transporter(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50503240(CHEMBL4445651)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetReduced folate transporter(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50503240(CHEMBL4445651)
Affinity DataIC50: 66nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed